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This medicine is used to assist in the relief of severe, persistent pain (such as due to cancer).

Oxycodone is an opioid analgesic. It works by altering how your body perceives and responds to pain in the brain.

These strengths may result in overdose (and maybe death) if taken by someone who has not been using opioids on a consistent basis.

Avoid using extended-release oxycodone to treat pain that is minimal or will resolve within a few days.

What are the risks of taking OxyCodone 40mg pills?

Individuals who abuse OxyContin risk developing tolerance for the drug, meaning they must take increasingly higher doses to achieve the same effects. Long-term abuse of the drug can lead to physical dependence and addiction. Individuals who become dependent upon or addicted to the drug may experience withdrawal symptoms if they cease using the drug.

Withdrawal symptoms associated with OxyContin dependency or addiction include restlessness, muscle and bone pain, insomnia, diarrhea, vomiting, cold flashes, and involuntary leg movements.

Individuals who take a large dose of OxyContin are at risk of severe respiratory depression that can lead to death. Inexperienced and new users are at particular risk, because they may be unaware of what constitutes a large dose and have not developed a tolerance for the drug.

In addition, OxyContin abusers who inject the drug expose themselves to additional risks, including contracting HIV (human immunodeficiency virus), hepatitis B and C, and other blood-borne viruses.

Pharmacodynamics

Oxycodone acts directly on a number of tissues not related to its analgesic effect. These tissues include the respiratory centre in the brain stem, the cough centre in the medulla, muscles of the pupils, gastrointestinal tract, cardiovascular system, endocrine system, and immune system.

Oxycodone’s effect on the respiratory centre is dose dependant respiratory depression. The action on the cough centre is suppression of the cough reflex. Pupils become miopic or decrease in size, peristalsis of the gastrointestinal tract slows, and muscle tone in the colon may increase causing constipation.

Endocrine effects may include increased prolactin, decreased cortisol, and decreased testosterone.